Aim: Some Emergency Departments use undiluted albuterol in nebulizers designed to conserve drug during exhalation. We compared the in vitro... View Article
Bronchodilator effects of salbutamol powder administered via Rotahaler and of terbutaline aerosol administered via Misthaler. A comparison study in children with asthma.
A study to compare the bronchodilator effect of salbutamol powder (Ventolin, 200 micrograms) administered via a Rotahaler (SR), with that... View Article
A NOVEL SPACER FOR IN-VENTILATOR CIRCUIT USE PROVIDES EFFICIENT MEDICATION DELIVERY FROM PRESSURIZED METERED DOSE INHALERS (PMDI)
BACKGROUND: Optimal delivery of aerosol medication to the ventilated patient is difficult to achieve efficiently. Although ‘T’-piece actuators are small... View Article
Overcoming Electrostatic Charge Retention in a New Valved Holding Chamber (VHC): In Vitro Performance Comparison with Current Devices
Particle deposition caused by electrostatic attraction to the walls of VHCs made from non-conducting polymer can significantly reduce pressurized metered... View Article
COMPARISON OF VALVED-HOLDING CHAMBER (VHC)-FACEMASK/MOUTHPIECE WITH SMALL VOLUME NEBULIZER-FACEMASK FOR BRONCHODILATOR DELIVERY
ABSTRACT Aerosolized medications now represent the standard-of-care for asthma. We report a preliminary study to test the hypothesis that treatment... View Article
INHALED MEDICATIONS FOR NEONATES AND SMALL CHILDREN VIA A NOVEL AEROSOL CHAMBER (VHC): LABORATORY SIMULATION OF DELIVERY OPTIONS
ABSTRACT BACKGROUND: Delivery of bronchodilators to infants and small children by pressurized metered-dose inhaler-holding aerosol valved holding chamber (pMDI-VHC) is... View Article
The efficacy of terbutaline inhaled from different aerosol systems was studied in 13 adult asthmatics. Terbutaline 1 mg was delivered... View Article
Sixty hospitalised children with asthma aged 1-5 years were randomised to spacer or nebuliser. A clinical score was measured at... View Article
Oropharyngeal candidiasis in patients treated with beclomethasone dipropionate delivered by metered-dose inhaler alone and with Aerochamber.
We compared the incidence of Candida infection, Candida colonization, and reduction in oral prednisone dose in patients with asthma treated... View Article
Rationing of medical services will be necessary if we do not develop a more rational and efficient health care system.... View Article