The bronchodilator response to metaproterenol sulfate delivered by metered-dose inhaler (MDI) with a spacer device (Aerochamber) and by jet nebulizer... View Article
BACKGROUND: Rates of death from asthma in the United States increased from 1978 until 1988 and have tended to stabilize... View Article
A Comparison of Inline MDI Actuators for Delivery of a Beta Agonist and a Corticosteroid with a Mechanically Ventilated Lung Model
EVTRODUCTION: The type of metered dose inhaler (MDI) actuator/adaptor as well as the type of drug used may influence the... View Article
BACKGROUND: Pressurized metered-dose inhalers with valved holding chambers and masks are commonly used for aerosol delivery in children. Drug delivery... View Article
Sixty hospitalised children with asthma aged 1-5 years were randomised to spacer or nebuliser. A clinical score was measured at... View Article
Salbutamol Delivery From a Hydrofluoroalkane Pressurized Metered-Dose Inhaler in Pediatric Ventilator Circuits
Study objectives: The aim of our study was to determine the in vitro delivery of salbutamol from a pressurized metered-dose... View Article
BACKGROUND: Prolonged treatment with inhaled steroids is recommended for long-term control of asthma in children; however, it can interfere with... View Article
Aerosol bronchodilator delivery methods. Relative impact on pulmonary function and cost of respiratory care.
Thirty-six acutely III, hospitalized patients with acute exacerbations of obstructive airway disease and a greater than 10% increase in forced... View Article
Comparison of bronchodilator responses and deposition patterns of salbutamol inhaled from a pressurised metered dose inhaler, as a dry powder, and as a nebulised solution.
The lung dose and deposition patterns of drug delivered by dry powder inhaler are not known. The effects of inhaling... View Article
BREATH-ACTUATED NEBULIZER DELIVERS BRONCHO-DILATOR MORE EFFICIENTLY THAN CONVENTIONAL JET NEBULIZER IN A SIMULATION OF AN ADULT TIDAL-BREATHING PATIENT
Rationale: To compare delivery of albuterol sulfate inhalation solution (2.5 mg/3 ml vial equivalent to 0.083% w/v albuterol, Zenith Goldline... View Article