BACKGROUND: Pressurized metered-dose inhalers with valved holding chambers and masks are commonly used for aerosol delivery in children. Drug delivery... View Article
Budesonide, a topically active corticosteroid, was administered in doses of 400 and 1,600 micrograms/day to 35 asthmatic adults, using a... View Article
Sixty hospitalised children with asthma aged 1-5 years were randomised to spacer or nebuliser. A clinical score was measured at... View Article
BACKGROUND: Prolonged treatment with inhaled steroids is recommended for long-term control of asthma in children; however, it can interfere with... View Article
Peak expiratory flow associated with change in positioning of the instrument: comparison of five peak flow meters.
To determine if peak expiratory flow (PEF) is altered by incorrect positioning of five peak flow meters (PFMs), 16 adults... View Article
The bronchodilator response to metaproterenol sulfate delivered by metered-dose inhaler (MDI) with a spacer device (Aerochamber) and by jet nebulizer... View Article
Response to bronchodilator drug administration by a new reservoir aerosol delivery system and a review of other auxiliary delivery systems.
Response to bronchodilator aerosols delivered by metered dose inhalers (MDI) depends in part upon the amount of drug depositing on... View Article
Topically active inhaled corticosteroid (IC) drugs are highly effective for chronic asthma. Formalized conceptions of "high, low or safe" dosages... View Article
Comparison of albuterol delivered by a metered dose inhaler with spacer versus a nebulizer in children with mild acute asthma.
OBJECTIVE: In children with mild acute asthma, to compare treatment with a single dose of albuterol delivered by a metered... View Article
The effects of changes in metered volume and propellant vapour pressure on the deposition of pressurized inhalation aerosols
The effects of changes in metered volume and propellant vapour pressure on the deposition of a pressurized inhalation aerosol have... View Article